Marfan on the Move

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Marfan on the Move

C ardiovascular characteristics in Marfan syndrome patients are caused by defects in the fibrillin-1 (FBN1) gene, encoding an extracellular matrix (ECM) protein present in elastic tissues, such as the heart and blood vessels. Of all the Marfan symptoms, the most life threatening is aortic dissection and rupture before the age of 40 years. There is no adequate treatment apart from aortic replace...

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ژورنال

عنوان ژورنال: Journal of the American Heart Association

سال: 2017

ISSN: 2047-9980,2047-9980

DOI: 10.1161/jaha.117.007465